Does Creatine Increase Testosterone Levels?

A shirtless young man at the gym, drinking a creatine shake after working out

Creatine has emerged as one of the most widely used supplements among fitness enthusiasts and athletes alike. Its popularity stems from its proven ability to enhance exercise performance, increase muscle mass, and improve overall physical function. However, many individuals are also curious about the potential relationship between creatine and testosterone, the primary male sex hormone that plays a crucial role in muscle growth, strength, and general well-being.

In this article, we’ll look at the complex relationship between creatine supplementation and testosterone levels. By examining the available scientific evidence, we’ll explore whether creatine has a direct impact on testosterone production or if its benefits are primarily derived from its well-established effects on exercise performance. 

Key Takeaways:

  • The direct effect of creatine supplementation on testosterone levels is unclear, with mixed results from available studies.
  • Creatine may indirectly support testosterone production by enhancing exercise performance and enabling greater training volume and intensity.
  • A holistic approach, including regular resistance training, a balanced diet, adequate sleep, stress management, and supplementation is essential for optimizing testosterone levels.
  • While creatine is generally safe and well-tolerated, proper dosage, cycling, and individual considerations are important to ensure optimal results and minimize potential side effects.

How Creatine Works

Creatine is a naturally occurring compound produced in the human body, primarily in the liver, kidneys, and pancreas. It is also found in some foods, such as meat, fish, and eggs. Creatine is stored mostly in the skeletal muscles, where it plays a crucial role in energy production during high-intensity exercises.

In the body, creatine combines with phosphate to form phosphocreatine (PCr). During intense physical activity, PCr donates its phosphate group to adenosine diphosphate (ADP) to create adenosine triphosphate (ATP), the primary energy currency of the cell. This process provides a rapid and efficient energy source for muscle contractions, especially during short bursts of high-intensity exercise.

Creatine supplementation has been extensively studied for its performance-enhancing effects. Research has consistently shown that creatine can increase muscle creatine stores, leading to improved strength, power output, and muscle mass. These benefits are particularly evident in activities that involve short, intense bouts of exercise, such as weightlifting, sprinting, and high-intensity interval training. Additionally, creatine has been found to reduce muscle damage and enhance recovery after intense workouts.

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Testosterone and Its Role

Testosterone is a steroid hormone primarily produced in the testicles of males and, to a lesser extent, in the ovaries of females. It belongs to a class of hormones called androgens, which are responsible for the development and maintenance of male characteristics. Testosterone production begins during puberty and reaches its peak in early adulthood, gradually declining with age.

Testosterone plays a vital role in various physiological processes, particularly in the development and maintenance of muscle mass, strength, and bone density. It stimulates protein synthesis, promoting muscle growth and repair. Additionally, testosterone has a significant impact on fat distribution, red blood cell production, and overall energy levels. In terms of sexual function, testosterone is essential for maintaining libido, erectile function, and sperm production.

Several factors can influence testosterone levels in the body. Age is a primary factor, with testosterone levels naturally declining by about 1% per year after the age of 30. Other factors that can affect testosterone production include:

  • Genetics: Some individuals may be genetically predisposed to lower testosterone levels.
  • Diet: A diet lacking in essential nutrients, such as zinc and vitamin D, may negatively impact testosterone production.
  • Exercise: Regular physical activity, particularly resistance training, has been shown to boost testosterone levels.
  • Sleep: Insufficient or poor-quality sleep can disrupt testosterone production.
  • Stress: Chronic stress can lead to elevated cortisol levels, which can suppress testosterone production.
  • Medical conditions: Certain health issues, such as obesity, type 2 diabetes, and hypogonadism, can result in lower testosterone levels.

Studies on Creatine and Testosterone

Study 1: Creatine supplementation in young rugby players

Methodology and participants: A study conducted on young male rugby players investigated the effects of creatine supplementation on hormone levels. Participants were divided into two groups: a creatine group receiving 20 grams of creatine daily for 5 days, followed by 5 grams per day for the remainder of the 14-day study, and a placebo group.

Results: While the creatine group experienced a significant increase in dihydrotestosterone (DHT) levels, a metabolite of testosterone, there was no significant change in total testosterone levels compared to the placebo group.

Study 2: Creatine supplementation in healthy, active men

Methodology and participants: In a study involving healthy, active men, participants were given either a creatine supplement or a placebo in conjunction with a resistance training program for 4 weeks.

Results: The creatine group showed a significant increase in testosterone levels after the resistance training program compared to the placebo group. However, it is important to note that the testosterone increase was observed in response to the training stimulus, and creatine supplementation alone was not responsible for the hormonal change.

Other studies showing no significant effect of creatine on testosterone

Several other studies have investigated the direct relationship between creatine supplementation and testosterone levels, without the confounding factor of resistance training. However, these studies have generally found no significant increase in testosterone levels as a result of creatine supplementation alone.

For example, a study examining the effects of creatine loading (20 grams per day for 7 days) on testosterone levels in male athletes found no significant changes in hormone levels compared to baseline values.

Overall, the available research suggests that while creatine may indirectly support testosterone production by enhancing exercise performance, it does not appear to have a direct, independent effect on testosterone levels in the absence of a training stimulus.

Indirect Effects of Creatine on Testosterone

Creatine’s role in improving exercise performance

  • Creatine supplementation has been consistently shown to enhance high-intensity exercise performance, such as weightlifting and sprinting.
  • By increasing the availability of phosphocreatine in muscle cells, creatine enables the rapid regeneration of ATP, the primary energy source for muscle contractions.
  • This increased energy availability allows for greater training volume and intensity, leading to improved strength and power output.

Relationship between intense resistance training and testosterone production

  • High-intensity resistance training has been demonstrated to stimulate the acute release of testosterone in men.
  • The magnitude of the testosterone response appears to be related to the volume and intensity of the resistance training session.
  • Chronic resistance training can also lead to long-term elevations in resting testosterone levels, particularly in previously untrained individuals.

Creatine’s potential to indirectly influence testosterone through enhanced workout capacity

  • By improving exercise performance and enabling greater training volume and intensity, creatine supplementation may indirectly support testosterone production.
  • The increased muscle mass and strength gained from creatine-enhanced training may also contribute to long-term elevations in resting testosterone levels.
  • However, it is important to note that the relationship between creatine, exercise performance, and testosterone is indirect and mediated by the training stimulus itself.

So, while creatine does not appear to directly increase testosterone levels, its ability to enhance high-intensity exercise performance may indirectly support testosterone production by enabling greater training volume and intensity. This indirect relationship is dependent on the individual’s training status and the specific exercise stimulus applied.

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Safety and Considerations

Creatine is generally considered safe for healthy individuals when taken at recommended doses. Long-term studies have shown no adverse effects from creatine supplementation for up to 5 years at doses of 10 grams per day.

Most reported side effects, such as gastrointestinal discomfort and muscle cramps, are anecdotal and not supported by well-controlled studies.

Importance of Proper Dosage and Cycling

The recommended creatine dose is 3-5 grams per day for maintenance. Higher doses may not provide additional benefits.

Creatine cycling, involving a loading phase followed by a maintenance phase and a rest period, is a common approach to optimize creatine stores and prevent the body from adapting to supplementation.

During the loading phase, a dose of 20-25 grams per day is typically divided into smaller doses for 5-7 days. The maintenance phase usually lasts 4-6 weeks, with a daily dose of 3-10 grams. A rest period of 2-4 weeks allows the body to reset and naturally produce creatine before starting a new cycle.

Individual Variations in Response to Creatine

 Some individuals may be non-responders to creatine supplementation due to genetic factors or pre-existing high muscle creatine content. Creatine supplementation may not be suitable for individuals with certain health conditions, such as kidney disease, liver disease, or diabetes.

Pregnant and breastfeeding women should avoid creatine supplementation due to limited safety data. Children and adolescents should consult a healthcare professional before taking creatine, although some studies suggest it may be safe when taken in recommended doses.

Alternative Ways to Boost Testosterone

Resistance training and high-intensity exercises

Engaging in regular resistance training, such as weightlifting, can stimulate testosterone production. High-intensity interval training (HIIT), which involves short bursts of intense exercise followed by periods of rest, has also been shown to boost testosterone levels.

Compound exercises that target multiple muscle groups, such as squats, deadlifts, and bench presses, are particularly effective for increasing testosterone.

Balanced Diet Rich in Protein and Healthy Fats

Consuming a diet high in protein, healthy fats, and complex carbohydrates can support optimal testosterone production. Foods that may boost testosterone include:

  • Oysters, which are rich in zinc, a mineral essential for testosterone production
  • Fatty fish, such as salmon and tuna, which contain vitamin D and omega-3 fatty acids
  • Leafy green vegetables, like spinach and kale, which provide magnesium
  • Eggs, particularly the yolks, which contain vitamin D and healthy fats
  • Ginger, which may enhance luteinizing hormone production and reduce oxidative stress

Additionally, limiting alcohol consumption and avoiding processed foods high in sugar and unhealthy fats can also help maintain healthy testosterone levels.

Adequate Sleep and Stress Management

Getting sufficient high-quality sleep, typically 7-8 hours per night, is crucial for maintaining optimal testosterone levels. Sleep deprivation and sleep disorders, such as obstructive sleep apnea, have been linked to decreased testosterone production.

Managing stress through techniques like meditation, deep breathing, and yoga can help reduce cortisol levels, which can negatively impact testosterone production when chronically elevated.

Natural Testosterone Supplements

Research shows that some natural supplements may help to boost testosterone levels. These  include:

  • Vitamin D: Healthy levels of vitamin D are associated with higher testosterone levels. Vitamin D supplementation may be beneficial, especially for those who are deficient.
  • Zinc: Zinc is essential for male reproductive health and testosterone production. Oysters, beef, beans, and some breakfast cereals are good sources of zinc. Supplementation may help raise testosterone levels, particularly in those with zinc deficiencies.
  • Ashwagandha: This herb, traditionally used in Ayurvedic medicine, has been shown in some studies to increase testosterone levels in healthy males. It may work by reducing stress and cortisol levels, which can interfere with testosterone production.
  • Ginger: Some studies, primarily in animals, suggest that ginger may help boost testosterone levels by working as an antioxidant and normalizing blood glucose levels. In females, ginger may stimulate the production of luteinizing hormone, which supports reproductive cycles.
  • D-Aspartic Acid: This amino acid may stimulate the release of hormones that prompt the body to produce more testosterone, although research results are mixed.
  • Fenugreek: Fenugreek is another herb that may support healthy testosterone levels, although more research is needed to confirm its effectiveness.

It’s important to note that while these supplements show promise, the research is not entirely conclusive, and individual results may vary. It’s always best to consult with a healthcare professional before starting any new supplement regimen to ensure safety and rule out potential interactions with existing medications or health conditions.

By incorporating a combination of regular exercise, a balanced diet, adequate sleep, stress management, and targeted supplementation when necessary, individuals may be able to naturally support and optimize their testosterone levels for improved overall health and well-being.

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The relationship between creatine supplementation and testosterone levels is complex and not fully understood. While some studies suggest that creatine may increase testosterone or its more active form, DHT, the evidence is mixed and inconclusive. Most studies have found no significant direct effect of creatine on total or free testosterone levels.

Although creatine supplementation may offer some indirect benefits for testosterone production through enhanced exercise performance, its direct effects on hormone levels remain unclear. A comprehensive lifestyle approach, including regular resistance training, a balanced diet, and healthy sleep and stress management habits, is likely the most effective way to naturally support and optimize testosterone levels.

As always, consulting with a healthcare professional is recommended for personalized guidance and to address any specific concerns or individual needs.

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